If you’ve ever wished your dog could live longer, science is catching up. By 2026, two groundbreaking longevity drugs are expected to hit the market—marking a historic milestone in canine health.

Developed by biotech company Loyal, these FDA-recognized treatments are designed to extend your dog’s lifespan and improve their quality of life. Here’s everything you need to know about these revolutionary dog longevity treatments—and what they could mean for your pet.

🧬 What Are These Dog Longevity Drugs?

✅ LOY-001 – For Large Breed Dogs

Form: Injection Target: Large and giant breeds like Great Danes, German Shepherds, and Labs Function: Lowers IGF-1, a hormone linked to faster aging in large dogs Expected Release: 2026

✅ LOY-002 – For Senior Dogs

Form: Daily oral tablet Target: Senior dogs of most sizes Function: Mimics the effects of calorie restriction to support metabolic and cognitive health Expected Release: Late 2025 (pending conditional FDA approval)

Both treatments are aimed at extending healthspan—the number of healthy, active years your dog can enjoy.

📈 Why This Matters for Dog Owners

These anti-aging drugs for dogs could be a game-changer.

Unlike traditional dog health supplements that focus on treating specific issues like joints or digestion, LOY-001 and LOY-002 are designed to slow down aging itself.

That means:

🐕‍🦺 More years with your best friend ❤️ Better quality of life in old age 🧠 Improved cognitive and physical performance

🧪 Backed by the FDA

In 2023 and 2025, both drugs received a rare FDA designation: “reasonable expectation of effectiveness.”

This fast-tracks the path toward conditional approval, allowing dogs to benefit while long-term trials continue.

🔬 A Look at the Science Behind It

IGF-1 Reduction (LOY-001): Research has shown large-breed dogs age faster due to elevated levels of IGF-1. Lowering this hormone could slow the biological clock. Calorie Restriction Mimetic (LOY-002): Mimicking fasting or low-calorie diets has been shown to extend lifespan in various species, including mice and primates.

🛒 When & Where Can You Get It?

While not yet available, Loyal plans to release:

LOY-002 in late 2025 LOY-001 in early 2026

They will be available through veterinarians, with usage monitored in real-time via ongoing studies.

💡 Final Thoughts from Chrysidis Pet Care

As dog lovers, we all want more time with our pets. With these innovative dog longevity drugs, that wish may soon become reality.

Stay tuned to Chrysidis.com for updates on pet wellness, canine longevity, and breakthroughs in veterinary science.